Our paper on ECLiPSE is now online in Nature Methods

We are excited to see ECLiPSE, our feature extraction, quantification and classification pipeline for 2D and 3D SMLM data online in Nature Methods! Congratulations Siewert and all co-authors! We are excited about what ECLiPSE can do for the analysis of super-resolution data and hope everyone can try it out for their science! Read the paper here: https://www.nature.com/articles/s41592-024-02414-3

Welcome Jailynn Harke!

We are pleased to have Jailynn Harke, who obtained her PhD in Eric Joyce’s lab here at Penn, join our lab as a postdoctoral fellow. Jailynn will work on using advanced imaging technologies to study 4D genome organization and how it relates to genome function!

Goodbye Angel and Qing!

We had a bittersweet lab gathering to bid farewell to Angel and Qing and wish them the best on their next journey.

Very excited to send Qing off to start her independent PI position at the University of Nebraska and looking forward to watching the exciting science that will come out of her lab.

Best of luck to both of you! We will miss you.

Welcome Victor Xing!

Lakadamyali lab keeps growing. We are pleased to welcome Victor, who has decided to join the lab as a PhD student after having completed his rotation in the lab!

Triple celebration in the Lakadamyali Lab

We celebrated Jose-Angel Martinez Sarmiento successfully defending his thesis! Hannah Kim passed her prelims with flying colors to officially become a PhD candidate. And Adriana Naomi Santiago-Ruiz got her NIH F31 fellowship funded! What a week! Congratulations to Angel, Hannah and Adriana!

Welcome Solon Andrades Da Rosa

We have a new visiting PhD student from the ICBS/UFRGS in Brazil. Solon will study the heterogeneity of senescent cells in glioblastoma cancer using super-resolution microscopy. We are excited to have him in the lab

Our paper on the impact of chemomechanical cues on chromatin in Nature BME

Our collaborative work with the labs of Su Chin Heo, Rob Mauck, Vivek Shenoy and Jason Burdick showing how degenerative chemomechanical cues in disease impact chromatin spatial organization is out in Nature Biomedical Engineering. Congratulations to all authors. This has been a fun collaboration. Read here the paper:

https://www.nature.com/articles/s41551-022-00910-5?fbclid=IwAR1vFx75OCEOTHfYchn2IRZHXKWoNYdhsnr-5KKRmf41u1qMO0va0V68MvI

And the highlight in Penn Medicine News:

https://www.pennmedicine.org/news/news-releases/2022/august/the-locked-library-disease-causes-cells-to-reorder-their-dna-incorrectly?fbclid=IwAR3qva_SZlUHogG6LdVeLNwxj-fxq8mUNFIZoqgeRTMeUbZklC5hoL2uUDg