January 5, 2021 — Congratulations to graduate student Angel on his wedding!
Preprint Alert
January 1, 2021 — “Chemo-Mechanical Cues Modulate Nano-Scale Chromatin Organization in Healthy and Diseased Connective Tissue Cells” by Heo et al is out in bioRxiv: https://www.biorxiv.org/content/10.1101/2021.04.27.441596v1.abstract
Latest paper in Cell Reports!
January 1, 2021 — Former graduate student Pablo-Gomez Garcia publishes his first author paper in Cell Reports studying the dynamics of single nucleosomes: https://www.sciencedirect.com/science/article/pii/S221112472031603X
UO1 Grant from 4DN
December 1, 2020 — Lakadamyali lab receives a UO1 grant from the 4DN consortium to study nuclear organization in disease in collaboration with Cremins, Joyce, Jain and Vahedi labs at Penn
Collaboration with Zaret lab out in Molecular Cell!
August 20, 2020 — Our collaborative paper with the Zaret lab on transcription factor mobility in the nucleus is out in Molecular Cell: https://www.sciencedirect.com/science/article/pii/S1097276520303579
Melike's Promotion
July 1, 2020 — Melike has been promoted to Associate Professor at Penn! She is grateful to all her lab members past and present for their contributions as well as all her scientific mentors, collaborators at Penn and beyond!
Collaborative work with Mauck Lab in Science Advances
June 1, 2020 — We are thrilled to have contributed to this paper out by our close collaborators Su Chin Heo and Rob Mauck in Science Advances: https://advances.sciencemag.org/content/6/25/eaax5083.abstract
Welcome Qing!
April 1, 2020 — We welcome Qing Tang, a new postdoc in the lab who will be studying microtubule PTMs and intracellular transport
Perspective on Genome Organization in Nature Methods
March 2, 2020 — A perspective article on genome organization from the lab is out in Nature Method: https://www.nature.com/articles/s41592-020-0758-3
Preprint alert
January 1, 2020 ORP1L regulates dynein clustering on endolysosmal membranes in response to cholesterol levels by Thakur et al is out in bioRxiv: https://www.biorxiv.org/content/10.1101/2020.08.28.273037v5.abstract
NIH-NIGMS-RM1
The Lakadamyali lab is excited to receive a collaborative RM1 grant from NIH-NIGMS, together with the Ostap, Holzbaur, & Dominguez labs at UPenn, and the Vavylonis lab at Lehigh University! We will study the mechanisms of mitochondrial transport from atomistic to cell biological level.
Read MoreInstitute on Aging Pilot Grant
The Lakadamyali lab is excited to receive a pilot grant from the IOA at UPenn to study tau aggregation using super-resolution microscopy!
Read MoreCollaboration with Epstein Lab in eLife
Our collaborative work with the Epstein lab on the role of H3K9me2 on heterochromatin positioning is published in eLife. Congratulations to Andrey and all the co-authors.
NIH-NIGMS RO1
Melike receives an RO1 from the NIH-NIGMS for developing new methods for quantifying protein stoichiometry with super-resolution microscopy! Congratulations to the Lakadamyali lab for this great achievement!
NSF-EFRI-CEE Grant
Melike receives an NSF-EFRI-CEE grant together with Carlos Castro (Ohio State University), Michael Poirier (Ohio State University) and Laszlo Tora (IGBMC) to engineer new DNA-origami tools for visualizing and manipulating chromatin. Congratulations to the whole team and excited to officially kick off this exciting collaboration.
Welcome Angel - Visiting Student
We welcome Angel, a visiting student from the Cosma lab at CRG, Barcelona. Excited to have him here to do super-resolution imaging of chromatin remodeling in reprogramming!
Histone Tail Acetylation Impacting Chromatin Structure in Nucleic Acids Research
Check out our new paper on how histone tail acetylation impacts chromatin structure, published in Nucleic Acids Research.
Welcome Alex - Undergraduate Student
We welcome Alex Zhou from the Physics Department as a new undergraduate student in the Lakadamyali lab.
Invariant Quantification of Dynein Stoichiometry in Biophysical Journal
Lakadamyali lab publishes a paper on imaging invariant quantification of dynein stoichiometry in the Biophysical Journal!
Detyrosinated Microtubules in Autophagy in JCB
Congratulations to Nitin for publishing his paper on the role of detyrosinated microtubules in autophagy in JCB!