Lakadamyali lab is happy to welcome Hannah Kim from the BMB Graduate Group who officially joined the lab as a PhD student.
Big Weekend in the Lakadamyali lab
Lakadamyali lab had a double celebration over the long 4th of July weekend. We celebrated Melina’s wedding - Congratulations Melina and Nick - and we celebrated the arrival of Angel’s baby on the very same day, Dara Valentina - Congratulations Angel and Yazmin -
Congratulations Dr. Gyparaki
Big congratulations to Melina Gyparaki, the first student to join the Lakadamyali lab at Penn, for successfully defending her thesis and becoming the first Penn graduate of the Lakadamyali lab. We are very proud of what you have accomplished over these years!
Angel wins first place poster award!
Congratulations to Angel who won the first place poster award at the IRM retreat. Angel was up against some tough competition and came out ahead. Great job Angel!
Congratulations Siewert!
Siewert's paper from the LASIRE lab (University of Lille, France) was selected for the Editor's choice for Super-resolution microscopy collection in Scientific Reports. Congratulations Siewert!
Open Postdoc Positions
We have open postdoc positions to work at the interface of advanced microscopy and cell biology of intracellular transport, protein aggregates and the nucleus. Interested individuals should email their CV and cover letter to Melike.
Our new review paper out in Molecular Cell!
January 2022 — Our new review paper on super-resolution is out in Molecular Cell. Huge congratulations to Charlie, Adriana and Qing on the big effort that made this review possible. You can check it out here: https://www.sciencedirect.com/science/article/pii/S1097276521010844?via%3Dihub
Welcome Siewert!
September 13, 2021 — We welcome Siewert Hugelier to the lab. Siewert will continue Arian’s legacy on the development of computational tools for super-resolution microscopy and single molecule imaging. We are thrilled to have him join the team!
Goodbye Arian!
August 27, 2021 — We are sad to say goodbye to Arian Arab but excited for his next steps and his transition to the FDA. Arian made a huge impact to the lab’s computational development efforts during his time in the lab and he will be missed!
Collaborative paper with Cosma lab out in Molecular Cell
August 5, 2021 — Our paper on transcription and genome organization in collaboration with the Cosma lab at CRG is out in Molecular Cell: https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00456-1
Highlight by Shah and Nora: https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00581-5
Cover Art: https://www.cell.com/molecular-cell/issue?pii=S1097-2765(20)X0016-5#closeFullCover
Congratulations Adriana!
July 2, 2021 — Congratulations to graduate student Adriana for being selected to the Structural Biology Training Grant!
New primer on Super-resolution out in Nature Reviews Method Primers
June 3, 2021 — Our primer on Single-molecule localization microscopy in collaboration with Christophe Zimmer, Markus Sauer, Ralf Jungmann and Suliana Manley is out in Nature Reviews Methods Primers. Proud of Melina for spearheading the lab’s contribution to this primer: https://www.nature.com/articles/s43586-021-00038-x
Prelims were passed with flying colors!
May 26, 2021 — Triple congratulations to Adriana, Charlie and Patty for unanimously passing their prelim exams!
Collaborative paper with Xiao lab in Nature Methods
May 31, 2021 — Very happy to see this collaborative paper with the Jie Xiao lab at Johns Hopkins out in Nature Methods. We helped develop a method for reducing blinking and over-counting artefacts in SMLM. Congrats to all involved and in particular Shreyasi Thakur from the Lakadamyali lab for spearheading the validation studies: https://www.nature.com/articles/s41592-021-01154-y
Our collaborative paper with Holzbaur and Ostap labs out in MBoC
April 19, 2021 — Our paper on Cega: a new tool for segmenting and identifying moving single molecules in noisy experiments is out in MBoC and has been selected as a Highlight by MBoC. This has been a super fun collaboration with the labs of Mike Ostap and Erika Holzbaur at Penn. Congratulations Erin and Peter: https://www.molbiolcell.org/doi/full/10.1091/mbc.E20-11-0744
CMT Study Section
April 15, 2021 — Melike becomes a standing member of the Cellular and Molecular technologies (CMT) Study Section at the NIH. She is excited to do her part to serve this community.
Our paper on Tau aggregates just out in PNAS
March 29, 2021 — Our paper on super-resolution imaging of tau aggregation is out in PNAS! Congratulations to Melina, Elena, Arian and Adriana! https://www.pnas.org/content/118/19/e2021461118.short?rss=1
Highlight in PNAS: https://www.pnas.org/content/118/19/eiti1921118
Highlight by Penn Medicine: https://www.pennmedicine.org/news/news-releases/2021/may/new-method-identifies-tau-aggregates-occurring-in-healthy-body-structures
Congratulations Melina for rocking it again!
March 17, 2021 — Congratulations to Melina for receiving a SAS Dissertation Completion fellowship!
Congratulations Melina!
February 24, 2021 — Graduate student Melina Gyparaki receives an SRAA Poster Award at the Biophysical Society Meeting
Collaborative work with Blobel lab out in Cell Reports
February 2, 2021 — Our collaborative paper with the Blobel lab on CTCF dynamics is out in Cell Reports: https://www.sciencedirect.com/science/article/pii/S2211124721000966